Sylvan is a Board-certified internist and geriatrician with broad experience in HIV disease and over 24 years of private practice at Pennsylvania Hospital (Philadelphia PA). He has worked as a Principal Investigator in the first-in-man Clinical Pharmacology Units for GlaxoSmithKline (GSK) and AstraZeneca.  Sylvan also worked in Pharmacovigilance with GSK and was the Medical Director for Luitpold Pharmaceuticals.

He has functioned as a physician adviser to hospitals nationwide performing second level utilization reviews, and was the trainer of physicians and nurses at Executive Health Resources (Newtown Square PA).

Sylvan currently volunteers at the Franklin Institute (Philadelphia PA) and Family Community Service of Delaware County in Media PA.  He serves on the Ritual Committee at Congregation Adath Israel (Merion PA).